KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED1
All Species:
18.48
Human Site:
S1548
Identified Species:
36.97
UniProt:
Q15648
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15648
NP_004765.2
1581
168478
S1548
D
Q
S
L
S
M
T
S
N
T
I
L
S
A
D
Chimpanzee
Pan troglodytes
XP_001172395
1581
168474
S1548
D
Q
T
L
S
M
T
S
N
T
I
L
S
A
D
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537654
1583
168625
S1550
D
Q
S
L
S
M
T
S
N
T
I
L
S
T
D
Cat
Felis silvestris
Mouse
Mus musculus
Q925J9
1575
167122
N1542
D
P
T
A
S
V
T
N
N
P
I
L
S
A
D
Rat
Rattus norvegicus
NP_001127833
1567
166392
N1534
D
Q
T
S
S
M
T
N
N
P
I
L
S
A
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521297
422
46589
L402
L
Q
F
E
V
C
P
L
S
D
S
C
F
S
V
Chicken
Gallus gallus
XP_418125
1594
169410
S1561
D
Q
S
L
S
M
A
S
S
A
I
L
S
A
E
Frog
Xenopus laevis
Q6INP8
1570
165663
G1540
D
P
T
M
A
M
S
G
G
S
M
M
S
S
D
Zebra Danio
Brachydanio rerio
XP_700209
1694
176982
S1662
E
T
S
V
S
L
L
S
S
E
R
S
S
R
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VP05
1475
149513
T1455
G
L
L
N
L
S
S
T
A
G
T
P
S
A
D
Honey Bee
Apis mellifera
XP_395879
1811
193227
V1772
P
A
S
P
S
V
S
V
H
I
V
K
S
P
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786427
2421
258175
S2094
S
K
M
P
S
M
S
S
K
K
P
D
S
K
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
N.A.
98
N.A.
94.4
93.9
N.A.
24.4
87.6
72.5
56.4
N.A.
22
24.4
N.A.
25.7
Protein Similarity:
100
100
N.A.
98.9
N.A.
97.1
96.5
N.A.
25.7
93.5
81.7
69
N.A.
38.9
41.1
N.A.
38.5
P-Site Identity:
100
93.3
N.A.
93.3
N.A.
60
73.3
N.A.
6.6
73.3
26.6
26.6
N.A.
20
20
N.A.
26.6
P-Site Similarity:
100
100
N.A.
93.3
N.A.
80
86.6
N.A.
20
86.6
80
53.3
N.A.
33.3
46.6
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
9
9
0
9
0
9
9
0
0
0
50
9
% A
% Cys:
0
0
0
0
0
9
0
0
0
0
0
9
0
0
0
% C
% Asp:
59
0
0
0
0
0
0
0
0
9
0
9
0
0
59
% D
% Glu:
9
0
0
9
0
0
0
0
0
9
0
0
0
0
9
% E
% Phe:
0
0
9
0
0
0
0
0
0
0
0
0
9
0
0
% F
% Gly:
9
0
0
0
0
0
0
9
9
9
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
9
50
0
0
0
0
% I
% Lys:
0
9
0
0
0
0
0
0
9
9
0
9
0
9
0
% K
% Leu:
9
9
9
34
9
9
9
9
0
0
0
50
0
0
0
% L
% Met:
0
0
9
9
0
59
0
0
0
0
9
9
0
0
0
% M
% Asn:
0
0
0
9
0
0
0
17
42
0
0
0
0
0
0
% N
% Pro:
9
17
0
17
0
0
9
0
0
17
9
9
0
9
17
% P
% Gln:
0
50
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
9
0
0
9
0
% R
% Ser:
9
0
42
9
75
9
34
50
25
9
9
9
92
17
0
% S
% Thr:
0
9
34
0
0
0
42
9
0
25
9
0
0
9
0
% T
% Val:
0
0
0
9
9
17
0
9
0
0
9
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _